BioLife Solutions Reports Fourth Quarter and Full Year 2025 Financial Results from Continuing Operations
PR Newswire
BOTHELL, Wash., Feb. 26, 2026
Fourth quarter 2025 revenue from continuing operations of $24.8 million, up 20% year-over-year; Full year 2025 revenue of $96.2 million, up 29% year-over-year
GAAP gross margin of 63% and non-GAAP adjusted gross margin of 64% for the fourth quarter
GAAP net income of $2.1 million or $0.04 per share and adjusted EBITDA of $6.9 million, or 28% of total revenue for the fourth quarter
Expects 2026 revenue growth of $112.5 million to $115.0 million, up 17%-20% over 2025
Conference call begins at 4:30 p.m. Eastern time today
BOTHELL, Wash., Feb. 26, 2026 /PRNewswire/ -- BioLife Solutions, Inc. (Nasdaq: BLFS) ("BioLife" or the "Company"), a leading developer and supplier of cell processing tools and services for the cell and gene therapy ("CGT") market, today announced financial results for the fourth quarter and full year 2025, and introduced 2026 financial guidance.
"2025 was a transformative year for BioLife. We delivered 29% revenue growth, led by sustained strength in our biopreservation media franchise and completed a strategic divestiture that firmly established BioLife as a focused, pure-play cell processing company centered on high-value, recurring revenue. With a streamlined cost structure and a scaled core business, we are now realizing the operating leverage inherent in our model." said Roderick de Greef, BioLife's Chairman and CEO. "Looking to 2026, we expect growth across our portfolio, operating margin expansion, continued improvement in adjusted EBITDA, and full year GAAP profitability.
"Continued growth of the CGT end market – including new, unique therapy approvals, geographic expansions, a shift to earlier lines of treatment and additional indications for approved therapies – will further embed our gold-standard tools into more commercial therapies that drive demand. An improving biotech funding environment, strategic investment by large pharma, and ongoing clinical progress underscore this market's long-term attractiveness and provides a meaningful opportunity ahead for BioLife," he added.
Fourth Quarter 2025 Business Highlights
- Our biopreservation media is utilized in approximately 250 ongoing commercially sponsored CGT clinical trials in the U.S., representing a more than 70% market share. This includes over 30 Phase III trials, or nearly 80% of the late-stage CGT trials. Our CellSeal® vials and human platelet lysate ("hPL") products are used in over 35 clinical trials.
- Our biopreservation media is embedded in 16 unique commercial CGT products as of December 31, 2025, with expectations for 7 additional product approvals, including 5 unique therapies, geographic expansions, earlier lines of treatment, or new indications over the next 12 months. Our CellSeal cryogenic vials and hPL products are embedded into four approved therapies.
- On October 6, 2025, we completed the sale of evo, a previously wholly owned subsidiary operated under SAVSU Cleo Technologies, LLC (formerly known as SAVSU Technologies, Inc.), for an aggregate sales price of $25.5 million in cash.
Fourth Quarter and Full Year 2025 Financial Results from Continuing Operations
BioLife is presenting various financial metrics under U.S. generally accepted accounting principles (GAAP) and as adjusted (non-GAAP). BioLife completed the divestitures of evo in 2025 and Global Cooling, Inc., SciSafe, Inc. and Custom Biogenic Systems in 2024, and is presenting the below results as discontinued operations for all periods presented. All amounts, percentages, and disclosures for all periods presented in this press release reflect only the continuing operations of the Company unless otherwise noted.
REVENUE
- Total revenue for the fourth quarter of 2025 was $24.8 million, an increase of $4.0 million, or 20%, from $20.7 million for the fourth quarter of 2024.
- Total revenue for 2025 was $96.2 million, an increase of $21.6 million, or 29%, from $74.6 million for 2024.
GROSS MARGIN
- Gross margin (GAAP) for the fourth quarter of 2025 was 63% compared with 66% for the fourth quarter of 2024. Adjusted gross margin (non-GAAP) for the fourth quarter of 2025 was 64% compared with 67% for the fourth quarter of 2024.
- Gross margin (GAAP) for 2025 was 65% compared with 67% for 2024. Adjusted gross margin (non-GAAP) for 2025 was 66% compared with 69% for 2024.
OPERATING LOSS
- Operating loss (GAAP) for the fourth quarter of 2025 was $0.1 million, compared with $1.2 million for the fourth quarter of 2024. Adjusted operating income (non-GAAP) for the fourth quarter of 2025 was $0.9 million compared with adjusted operating loss (non-GAAP) of $0.2 million for the fourth quarter of 2024.
- Operating loss (GAAP) for 2025 was $16.6 million, compared with $4.5 million for 2024. Adjusted operating income (non-GAAP) for 2025 was $2.9 million compared with adjusted operating loss (non-GAAP) of $2.6 million for 2024.
NET INCOME / (LOSS)
- Net income (GAAP) for the fourth quarter of 2025 was $2.1 million, compared with net loss of $1.2 million for the fourth quarter of 2024. Adjusted net income (non-GAAP) for the fourth quarter of 2025 was $1.9 million compared with adjusted net loss (non-GAAP) of $0.1 million for the fourth quarter of 2024.
- Net loss (GAAP) for 2025 was $12.1 million, compared with $8.8 million for 2024. Adjusted net income (non-GAAP) for 2025 was $6.3 million compared with adjusted net loss (non-GAAP) of $2.9 million for 2024.
NET INCOME / (LOSS) PER SHARE
- Net income per share (GAAP) for the fourth quarter of 2025 was $0.04, compared with net loss per share of $0.03 for the fourth quarter of 2024.
- Net loss per share (GAAP) for 2025 was $0.25, compared with $0.19 for 2024.
ADJUSTED EBITDA
- Adjusted EBITDA, a non-GAAP measure, for the fourth quarter of 2025 was $6.9 million, or 28% of revenue, compared with $3.7 million, or 18% of revenue, for the fourth quarter of 2024.
- Adjusted EBITDA, a non-GAAP measure, for 2025 was $25.0 million, or 26% of revenue, compared with $13.3 million, or 18% of revenue, for 2024.
CASH, CASH EQUIVALENTS, AND MARKETABLE SECURITIES
- Cash, cash equivalents, and marketable securities as of December 31, 2025, were $120.2 million. The Company received net proceeds of $23.5 million in cash from the sale of evo during October 2025.
(As a result of presenting amounts in millions, rounding differences may exist in the percentages above.) |
2026 Financial Guidance
BioLife is introducing 2026 financial guidance as follows:
- Revenue of $112.5 million to $115.0 million, representing growth of 17% to 20% compared with 2025 revenue from continuing operations;
- Gross margin (GAAP) in the mid-60% range, adjusted gross margin (non-GAAP) in the mid-60% range;
- Net income (GAAP) for the full year; and
- Continued expansion of adjusted EBITDA margin (non-GAAP).
Conference Call & Webcast
Management will discuss the Company's financial results, provide a general business update and answer questions during a conference call and live webcast today at 4:30 p.m. ET (1:30 p.m. PT).
To access the webcast, log onto the Investor Relations page of the BioLife website at https://www.biolifesolutions.com/earnings. In addition, the conference call will be accessible by dialing toll-free 1-833-630-0431 or 1-412-317-1808 for international callers. A webcast replay will be available approximately two hours after the call ends and will be archived on https://investors.biolifesolutions.com/ for 90 days.
About BioLife Solutions
BioLife is a leading developer and supplier of cell processing tools and services for the CGT market. Our expertise facilitates the commercialization of new therapies by supplying solutions that maintain the health and function of biologic materials during the collection, development, manufacturing and distribution. For more information, please visit www.biolifesolutions.com, and follow BioLife on LinkedIn and X.
Cautions Regarding Forward Looking Statements
Certain statements contained in this press release are not historical facts and may be forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as "plans," "expects," "believes," "anticipates," "designed," "may," "estimate," "guidance," and similar words are intended to identify forward-looking statements. Forward-looking statements are based on our current expectations and beliefs, and involve a number of risks and uncertainties that are difficult to predict and that could cause actual results to differ materially from those stated or implied by the forward-looking statements. A description of certain of these risks, uncertainties and other matters can be found in filings we make with the U.S. Securities and Exchange Commission, all of which are available at www.sec.gov. Because forward-looking statements involve risks and uncertainties, actual results and events may differ materially from results and events currently expected by us. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. We undertake no obligation to publicly update these forward-looking statements to reflect events or circumstances that occur after the date hereof or to reflect any change in its expectations with regard to these forward-looking statements or the occurrence of unanticipated events.
Non-GAAP Measures of Financial Performance
To supplement our financial statements, which are presented on the basis of U.S. generally accepted accounting principles (GAAP), the following non-GAAP measures of financial performance are included on a consolidated basis in this release: adjusted gross margin, adjusted operating expenses, adjusted operating income/(loss), adjusted net income/(loss), earnings before interest, taxes, depreciation and amortization (EBITDA), and adjusted EBITDA. A reconciliation of GAAP to adjusted non-GAAP financial measures is included as an attachment to this press release.
We believe these non-GAAP financial measures are useful to investors in assessing our operating performance. We use these financial measures internally to evaluate our operating performance and for planning and forecasting of future periods. We also believe it is in the best interests of investors to provide this non-GAAP information.
While we believe these non-GAAP financial measures provide useful supplemental information to investors, there are limitations associated with the use of these non-GAAP financial measures. These non-GAAP financial measures may not be reported by competitors, and they may not be directly comparable to similarly titled measures of other companies due to differences in calculation methodologies. The non-GAAP financial measures are not an alternative to GAAP information and are not meant to be considered in isolation or as a substitute for comparable GAAP financial measures. They should be used only as a supplement to GAAP information and should be considered only in conjunction with our consolidated financial statements prepared in accordance with GAAP.
Media & Investor Relations
At the Company
Troy Wichterman
Chief Financial Officer
(425) 402-1400
twichterman@biolifesolutions.com
Investors
Alliance Advisors IR
Jody Cain
(310) 691-7100
jcain@allianceadvisors.com
BIOLIFE SOLUTIONS, INC. | |||||||
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS | |||||||
(Unaudited, amounts in thousands, except share and per share amounts) | |||||||
Three Months Ended | Year Ended December 31, | ||||||
(In thousands, except per share and share data) | 2025 | 2024 | 2025 | 2024 | |||
Revenue | $ 24,764 | $ 20,715 | $ 96,214 | $ 74,647 | |||
Cost of revenue | 9,248 | 7,070 | 34,096 | 24,551 | |||
Gross profit | 15,516 | 13,645 | 62,118 | 50,096 | |||
Operating expenses: | |||||||
General and administrative | 11,020 | 11,476 | 45,520 | 40,627 | |||
Sales and marketing | 2,444 | 2,087 | 9,850 | 8,932 | |||
Research and development | 2,066 | 1,183 | 7,566 | 4,751 | |||
IPR&D expense | — | — | 15,521 | — | |||
Intangible asset amortization | 66 | 66 | 263 | 263 | |||
Total operating expenses | 15,596 | 14,812 | 78,720 | 54,573 | |||
Operating loss | (80) | (1,167) | (16,602) | (4,477) | |||
Other income (expense): | |||||||
Interest income (expense), net | 831 | (24) | 2,706 | (766) | |||
Other income | 1,184 | — | 1,815 | 494 | |||
Change in fair value of investments | — | — | — | (4,074) | |||
Total other income (expense), net | 2,015 | (24) | 4,521 | (4,346) | |||
Income (loss) before income tax (benefit) expense | 1,935 | (1,191) | (12,081) | (8,823) | |||
Income tax (benefit) expense | (173) | 24 | 49 | (38) | |||
Income (loss) from continuing operations | $ 2,108 | $ (1,215) | $ (12,130) | $ (8,785) | |||
Discontinued operations: | |||||||
Income from discontinued operations before income tax expense | 8,961 | 13,460 | 7,535 | (11,267) | |||
Income tax (benefit) expense | — | (33) | — | 132 | |||
Income from discontinued operations | $ 8,961 | $ 13,493 | $ 7,535 | $ (11,399) | |||
Net income (loss) | $ 11,069 | $ 12,278 | $ (4,595) | $ (20,184) | |||
Earnings (loss) per share - Basic: | |||||||
Continuing operations | $ 0.04 | $ (0.03) | $ (0.25) | $ (0.19) | |||
Discontinued operations | $ 0.19 | $ 0.29 | $ 0.16 | $ (0.25) | |||
Net income (loss) | $ 0.23 | $ 0.26 | $ (0.09) | $ (0.44) | |||
Earnings (loss) per share - Diluted: | |||||||
Continuing operations | $ 0.04 | $ (0.03) | $ (0.25) | $ (0.19) | |||
Discontinued operations | $ 0.18 | $ 0.28 | $ 0.15 | $ (0.25) | |||
Net income (loss) | $ 0.22 | $ 0.25 | $ (0.10) | $ (0.44) | |||
Weighted average shares used to compute net loss per share attributable to | |||||||
Basic | 48,144,415 | 46,648,902 | 47,753,824 | 46,067,073 | |||
Diluted | 49,009,286 | 48,032,700 | 48,645,084 | 46,067,073 | |||
BIOLIFE SOLUTIONS, INC. | |||||||
CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS | |||||||
(Unaudited, amounts in thousands) | |||||||
Three Months Ended | Year Ended | ||||||
(In thousands) | 2025 | 2024 | 2025 | 2024 | |||
Net income (loss) | $ 11,069 | $ 12,278 | $ (4,595) | $ (20,184) | |||
Other comprehensive income | 1 | 61 | 108 | 18 | |||
Comprehensive income (loss) | $ 11,070 | $ 12,339 | $ (4,487) | $ (32,506) | |||
BIOLIFE SOLUTIONS, INC. | |||
CONDENSED CONSOLIDATED BALANCE SHEET INFORMATION | |||
(Unaudited, amounts in thousands) | |||
(In thousands) | December 31, | December 31, | |
Cash, cash equivalents, and marketable securities | $ 120,177 | $ 105,364 | |
Working capital | 113,582 | 116,027 | |
Current assets | 136,561 | 144,177 | |
Current assets, discontinued operations | — | 4,584 | |
Total assets | 405,884 | 380,852 | |
Total assets, discontinued operations | — | 18,635 | |
Current liabilities | 22,979 | 32,118 | |
Current liabilities, discontinued operations | — | 616 | |
Long-term obligations | 11,017 | 17,766 | |
Long-term obligations, discontinued operations | — | 78 | |
Accumulated deficit | (339,696) | (335,101) | |
Total shareholders' equity | $ 371,888 | $ 348,909 | |
BIOLIFE SOLUTIONS, INC. | |||
CONDENSED CONSOLIDATED STATEMENT OF CASH FLOWS INFORMATION | |||
(Unaudited, amounts in thousands) | |||
Year Ended December 31, | |||
(In thousands) | 2025 | 2024 | |
Net cash provided by operating activities | $ 20,115 | $ 8,431 | |
Net cash (used in) provided by investing activities | (71,539) | 58,300 | |
Net cash used in financing activities | (10,924) | (6,783) | |
Net decrease (increase) in cash and cash equivalents | $ (62,348) | $ 59,948 | |
Cash and cash equivalents – beginning of period | $ 95,386 | $ 35,438 | |
Cash and cash equivalents – end of period | 33,038 | 91,538 | |
Marketable securities | 87,139 | 13,826 | |
Total cash, cash equivalents, and marketable securities | $ 120,177 | $ 105,364 | |
BIOLIFE SOLUTIONS, INC. | |||||||
RECONCILIATION OF GAAP GROSS PROFIT TO NON-GAAP ADJUSTED GROSS MARGIN | |||||||
(Unaudited, amounts in thousands) | |||||||
Three Months Ended | Year Ended December 31, | ||||||
(In thousands) | 2025 | 2024 | 2025 | 2024 | |||
Revenue | $ 24,764 | $ 20,715 | $ 96,214 | $ 74,647 | |||
Cost of revenue | (9,248) | (7,070) | (34,096) | (24,551) | |||
GAAP GROSS PROFIT | $ 15,516 | $ 13,645 | $ 62,118 | $ 50,096 | |||
GAAP GROSS MARGIN | 63 % | 66 % | 65 % | 67 % | |||
ADJUSTMENTS TO GAAP GROSS PROFIT: | |||||||
Inventory reserve costs | — | — | — | 247 | |||
Loss (gain) on disposal of assets | — | 87 | (12) | 87 | |||
Intangible asset amortization | 259 | 241 | 1,044 | 968 | |||
NON-GAAP ADJUSTED GROSS PROFIT | $ 15,775 | $ 13,973 | $ 63,150 | $ 51,398 | |||
NON-GAAP ADJUSTED GROSS MARGIN | 64 % | 67 % | 66 % | 69 % | |||
BIOLIFE SOLUTIONS, INC. | |||||||
RECONCILIATION OF GAAP OPERATING EXPENSES TO NON-GAAP ADJUSTED OPERATING | |||||||
(Unaudited, amounts in thousands) | |||||||
Three Months Ended | Year Ended December 31, | ||||||
(In thousands) | 2025 | 2024 | 2025 | 2024 | |||
GAAP OPERATING EXPENSES | $ 15,596 | $ 14,812 | $ 78,720 | $ 54,573 | |||
ADJUSTMENTS TO GAAP OPERATING | |||||||
Acquisition and divestiture costs | (597) | (540) | (1,904) | (1,245) | |||
Severance costs | — | — | (732) | — | |||
IPR&D expense | — | — | (15,521) | — | |||
Intangible asset amortization | (325) | (307) | (1,307) | (1,231) | |||
Loss on disposal of assets | (11) | (129) | (1) | (129) | |||
Bad debt recovery | — | — | — | 979 | |||
NON-GAAP ADJUSTED OPERATING | $ 14,663 | $ 13,836 | $ 59,255 | $ 52,947 | |||
BIOLIFE SOLUTIONS, INC. | |||||||
RECONCILIATION OF GAAP OPERATING LOSS TO NON-GAAP ADJUSTED OPERATING INCOME | |||||||
(Unaudited, amounts in thousands) | |||||||
Three Months Ended | Year Ended December 31, | ||||||
(In thousands) | 2025 | 2024 | 2025 | 2024 | |||
GAAP OPERATING LOSS | $ (80) | $ (1,167) | $ (16,602) | $ (4,477) | |||
ADJUSTMENTS TO GAAP OPERATING | |||||||
Acquisition and divestiture costs | 597 | 540 | 1,904 | 1,245 | |||
Severance costs | — | — | 732 | — | |||
IPR&D expense | — | — | 15,521 | — | |||
Intangible asset amortization | 325 | 307 | 1,307 | 1,231 | |||
Loss on disposal of assets | 11 | 129 | 1 | 129 | |||
Bad debt recovery | — | — | — | (979) | |||
Inventory reserve costs | — | — | — | 247 | |||
NON-GAAP ADJUSTED OPERATING | $ 853 | $ (191) | $ 2,863 | $ (2,604) | |||
OPERATING MARGIN | — % | (6) % | (17) % | (6) % | |||
NON-GAAP ADJUSTED OPERATING | 3 % | (1) % | 3 % | (3) % | |||
BIOLIFE SOLUTIONS, INC. | |||||||
RECONCILIATION OF GAAP NET INCOME (LOSS) FROM CONTINUING OPERATIONS TO NON- | |||||||
(Unaudited, amounts in thousands) | |||||||
Three Months Ended | Year Ended December 31, | ||||||
(In thousands) | 2025 | 2024 | 2025 | 2024 | |||
NET INCOME (LOSS) FROM | $ 2,108 | $ (1,215) | $ (12,130) | $ (8,785) | |||
ADJUSTMENTS TO NET INCOME (LOSS) | |||||||
Acquisition and divestiture costs | 597 | 540 | 1,904 | 1,245 | |||
Severance costs | — | — | 732 | — | |||
IPR&D expense | — | — | 15,521 | — | |||
Intangible asset amortization | 325 | 307 | 1,307 | 1,231 | |||
Loss on disposal of assets | 11 | 129 | 1 | 129 | |||
Change in fair value of investments | — | — | — | 4,074 | |||
Income tax (benefit) expense | (173) | 24 | 49 | (38) | |||
Bad debt recovery | — | — | — | (979) | |||
Other expense (income) | (956) | 68 | (1,046) | (18) | |||
Inventory reserve costs | — | — | — | 247 | |||
NON-GAAP ADJUSTED NET INCOME | $ 1,912 | $ (147) | $ 6,338 | $ (2,894) | |||
BIOLIFE SOLUTIONS, INC. | |||||||
RECONCILIATION OF GAAP NET INCOME (LOSS) FROM CONTINUING OPERATIONS TO NON- | |||||||
(Unaudited, amounts in thousands) | |||||||
Three Months Ended | Year Ended December 31, | ||||||
(In thousands) | 2025 | 2024 | 2025 | 2024 | |||
NET INCOME (LOSS) FROM | $ 2,108 | $ (1,215) | $ (12,130) | $ (8,785) | |||
ADJUSTMENTS: | |||||||
Interest (income) expense, net | (831) | 24 | (2,706) | 766 | |||
Accretion of available-for-sale investments | (228) | (68) | (769) | (476) | |||
Income tax (benefit) expense | (173) | 24 | 49 | (38) | |||
Depreciation | 262 | 161 | 849 | 643 | |||
Intangible asset amortization | 325 | 307 | 1,307 | 1,231 | |||
NON-GAAP EBITDA | $ 1,463 | $ (767) | $ (13,400) | $ (6,659) | |||
OTHER ADJUSTMENTS: | |||||||
Share-based compensation (non-cash) | 5,804 | 3,748 | 21,272 | 15,282 | |||
Acquisition and divestiture costs | 597 | 540 | 1,904 | 1,245 | |||
Severance costs | — | — | 732 | — | |||
IPR&D expense | — | — | 15,521 | — | |||
Loss on disposal of assets | 11 | 129 | 1 | 129 | |||
Change in fair value of investments | — | — | — | 4,074 | |||
Bad debt recovery | — | — | — | (979) | |||
Other expense (income) | (956) | 68 | (1,046) | (18) | |||
Inventory reserve costs | — | — | — | 247 | |||
NON-GAAP ADJUSTED EBITDA | $ 6,919 | $ 3,718 | $ 24,984 | $ 13,321 | |||
NON-GAAP ADJUSTED EBITDA MARGIN | 28 % | 18 % | 26 % | 18 % | |||
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SOURCE BioLife Solutions, Inc.
